http://www.twnside.org.sg/title/bad.htm

"Abstract: The debate on evolution between the creationists and the
neo-Darwinists is not just sterile, it misses the central issue, which
is that neo-Darwinism is wrong and dangerous.

It is promoting and
misguiding a runaway technology that has the potential to destroy all
life on earth. It reinforces a worldview that undermines every single
moral value that makes us human.

It is also obstructing and preventing
the necessary shift to holistic ecological sciences that can connect to
the organic revolution rising from the grassroots all over the world,
which can truly regenerate the earth and revitalize the human spirit."
[...]
"The Central Dogma formalizes the four basic assumptions of genetic
determinism and give them material substance."[... ]
"These assumptions fit neatly with the dominant neo-Darwinian theory,
which says that all of marvelous life on earth evolved, and is still
evolving essentially by the natural selection of random genetic
mutations. Neo-Darwinism combines Darwin's theory of evolution by
natural selection with August Weismann's theory of the immortal,
inviolable germline, which, through Mendelian and molecular genetics
became the Central Dogma. So, there is supposed to be a 'Weismann's
barrier' forbidding environmental influences from changing the genes
directly, especially in the germ cells that give rise to the next
generation."
[...]
"Recently, molecular geneticist James Shapiro has joined the debate. He
is critical of neo-Darwinians like Richard Dawkins and John Maynard
Smith who are still clinging to the discredited paradigm.

"Localized
random mutation, selection operating "one gene at a time" (John Maynard
Smith's formulation), and gradual modification of individual functions
are unable to provide satisfactory explanation for the molecular data,
no matter how much time for change is assumed. There are simply too many
potential degrees of freedom for random variability and too many
interconnections to account for."
[...]
"There is a striking contrast between the DNA-centered Central Dogma and
the new genetics. The scientific findings have completely invalidated
genetic determinism. The new genetics is diametrically opposite to the
old static, reductionist view. It is radically holistic. The gene has a
very complex ecology consisting of the interconnected levels of the
genome, the physiology of the organism and its external environment.
Changes in the environment is transmitted inwards, and may alter the
genes themselves. Conversely, putting a new gene or new combination of
genes into an organism will create disturbance that may propagate out to
the external environment. Remember that the genes themselves can spread
by horizontal transfer to unrelated species, so the potential ecological
impacts are enormous."

"But the mainstream biology community has remained untouched by this
profound revolution. Dawkins' views have not changed much since his
first book. Worse yet, genetic determinism is rife, if only because it
is perfect for promoting genetic engineering biotechnology and selling
it to the public."