| Topic: |
Sociology > Depression |
| User: |
"jd023456" |
| Date: |
16 Sep 2006 11:35:49 AM |
| Object: |
Combining St. John's Wort and Prozac. |
Anyone have any personal information about this? In other words
looking for people that have tried this and want to learn what their
experience was.=20
Thanks.=20
Jd.=20
Reply =BB
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| User: "Bacon" |
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| Title: Re: Combining St. John's Wort and Prozac. |
16 Sep 2006 11:51:16 AM |
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On 16 Sep 2006 09:35:49 -0700, "jd023456" <jd023456@yahoo.com> wrote:
Anyone have any personal information about this? In other words
looking for people that have tried this and want to learn what their
experience was.
Thanks.
Jd.
Reply »
Prozac and St. John's Wort is so 90's. Time to move on to the good
stuff.
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| User: "Ivan Marsh" |
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| Title: Re: Combining St. John's Wort and Prozac. |
18 Sep 2006 09:52:11 AM |
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On Sat, 16 Sep 2006 09:35:49 -0700, jd023456 wrote:
Anyone have any personal information about this? In other words
looking for people that have tried this and want to learn what their
experience was.
Don't... unless your doctor tells you to... which he/she won't.
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| User: "Franz Bestuchev" |
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| Title: Re: Combining St. John's Wort and Prozac. |
16 Sep 2006 05:02:20 PM |
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jd023456 wrote:
Anyone have any personal information about this? In other words
looking for people that have tried this and want to learn what their
experience was.
Thanks.
Jd.
Reply »
--Potentially Dangerous:
http://en.wikipedia.org/wiki/Serotonin_syndrome
Serotonin syndrome, also hyperserotonemia, serotonergic syndrome and
sometimes Serotonin Storm, is an illness caused by an excess of
serotonin (5-hydroxytryptamine, or 5-HT) in the central nervous system,
brought about by the use of prescription or non-prescription drugs, or
combinations of these.
Causes
It is most often associated with high doses of serotonergic drugs, when
"normal" doses of different serotonergic agents are used in combination,
or when different types of antidepressants are changed without an
adequate washout period between drugs.
Less frequently it can be caused by moderate dosage of a single
serotonergeric drug,[1][2] or in combination with non-serotonergeric
drugs such as oxycodone,[3] erythromycin,[4] or St. John's Wort.[5]
If you wish to locate scientific papers search using the terms serotonin
syndrome and also serotonin toxicity, the term that is being used by
some informed researchers in this field.
[edit]
Diagnosis
Serotonin syndrome is rare, but it is a serious, potentially
life-threatening medical condition. However there is no lab test for the
condition, so diagnosis is by symptom observation. It may go
unrecognized because it is often mistaken for a viral illness, anxiety,
neurological disorder or worsening psychiatric condition.[6] Clinicians
must differentiate between serotonin syndrome and neuroleptic malignant
syndrome, which has similar symptoms. Patients taking serotonergic drugs
and who have sudden onset of the below symptoms should immediately seek
medical care.
Serotonin toxicity is a toxidrome (i.e. a characteristic picture) caused
by poisoning with serotonergic drugs. It is unique and hard to confuse
with other medical conditions. Much confusion has been produced by
muddling it with side effects from serotonergic drugs. These rarely, if
ever, become dangerous or fatal. Dangerous toxicity is usually only ever
caused by mixtures of drugs with different modes of action, most
commonly monoamine oxidase inhibitors combined with serotonin reuptake
inhibitors. A first step in understanding this complex topic is to
appreciate the spectrum concept of serotonin toxicity (see
www.psychotropical.com Serotonin toxicity: 3 Spectrum concept).
reference 1. Gillman, PK, A Review of Serotonin Toxicity Data:
Implications for the Mechanisms of Antidepressant Drug Action.
Biological Psychiatry, 2006. 59: p. 1046-51.
[edit]
Signs and symptoms
Symptoms may be classed into three groups:
* Cognitive effects: mental confusion, hypomania, agitation,
headache, coma.
* Autonomic effects: shivering, sweating, fever, hypertension,
tachycardia, nausea, diarrhea.
* Somatic effects: myoclonus/clonus (muscle twitching),
hyperreflexia, tremor.
Insomnia, sleep disruption, and unrefreshing sleep are also reported
symptoms, as well as itching and hives.
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