| Topic: |
Sociology > Depression |
| User: |
"Howian" |
| Date: |
04 Jul 2003 09:06:44 AM |
| Object: |
findings on depression |
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Genome survey finds depression genes
WASHINGTON, July 2 (Reuters) - U.S. researchers using the newly published human
gene map said on Wednesday they had identified 19 different genetic regions
linked with depression.
The findings could eventually lead to better treatments and screening for
depression and related conditions, such as addiction, a leading cause of
disability in the United States.
Dr. George Zubenko, a professor of psychiatry at the University of Pittsburgh
School of Medicine, and colleagues screened 81 families with members suffering
from recurrent, early-onset, major depressive disorder, which runs in families.
They found 19 regions on chromosomes that seem to be involved in the condition,
they reported in the American Journal of Medical Genetics. Further work should
be able to pinpoint the actual genes involved.
The information could eventually lead to tailored treatments for depression,
Zubenko said.
"For example, individuals with particular genetic markers in these regions may
respond better to particular current treatments than others," he said in a
statement.
Zubenko's team found some mutations seem to be sex-specific -- some for women
and at least one for men.
"Women are twice as likely as men to develop depression, and genetic
differences appear to account for some of that disparity," Zubenko said.
These could help explain why women seem more vulnerable to depression during
puberty, pregnancy and childbirth and menopause, Zubenko said.
They also noticed that people in families with these genetic changes tend to
live shorter lives.
People who had died in the 81 families were eight years younger when they died
than the average for the general population, the researchers found.
They found a five-fold increase in the proportion of babies who died in the
first year of life and several-fold increases in deaths by suicide, murder and
liver disease, although most of the deaths were from heart disease, cancer and
stroke.
The National Institute of Mental Health reported last month that 16 percent of
Americans -- more than 30 million people -- will suffer major depression at
some point in their lives, costing employers more than $30 billion in lost
productivity.
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| User: "Basil" |
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| Title: Re: findings on depression |
04 Jul 2003 08:41:14 PM |
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(Howian) wrote in message news:<20030704100644.02096.00000090@mb-m07.aol.com>...
<snip,snap,thwack>
this really isn't surprising. the genetic roots of depression have
been slowly uncovered over the past few years. what's surprising,
really, is that it's taken them *this* long to figure it out. after
all, how many of us have family members with depression? heaven
knows, both sides of my family are *riddled* with it and it was
painfully obvious since i was a wee tyke, regardless of whether or not
some physician gave his or her nihil obstat to the diagnosis.
what's *really* depressing, though, is *this*--
The National Institute of Mental Health reported last month that 16 percent of
Americans -- more than 30 million people -- will suffer major depression at
some point in their lives, costing employers more than $30 billion in lost
productivity.
note the emphasis on the *economic* effects. the 'oh so hard done to'
employer-angle is disgusting. personally, if i'm clinically
depressed, i don't give a rat's glute that my employer's nose is put
out of joint. you don't see them making that kind of emphasis--that
same angle--with diseases like cancer. just replace the words 'major
depression' with 'cancer' and you'll note the subtle bias displayed.
i've *never* seen a story tsk-tsk about the economic effects of cancer
on employers...:-(
--basil
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| User: "Whiskers" |
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| Title: Re: findings on depression |
04 Jul 2003 07:20:13 PM |
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In alt.support.depression on Friday 04 Jul 2003 3:06 pm, Howian
<howian@aol.com> wrote:
Want to send this story to another AOL member? Click on the heart at the
top of this window.
No hearts on my window :((
Genome survey finds depression genes
WASHINGTON, July 2 (Reuters) - U.S. researchers using the newly published
human gene map said on Wednesday they had identified 19 different genetic
regions linked with depression.
snip
Zubenko's team found some mutations seem to be sex-specific -- some for
women and at least one for men.
"Women are twice as likely as men to develop depression, and genetic
differences appear to account for some of that disparity," Zubenko said.
These could help explain why women seem more vulnerable to depression
during puberty, pregnancy and childbirth and menopause, Zubenko said.
Men seldom have Depression during pregnancy and childbirth, and I'm certain
genetics have something to do with that!
They also noticed that people in families with these genetic changes tend
to live shorter lives.
People who had died in the 81 families were eight years younger when they
died than the average for the general population, the researchers found.
Hmm ... Depression seems to run in my family, but we're a long-lived lot.
snip
Interesting. Thanks for posting it :))
--
-- ^^^^^^^^^^ Interested in Citroens?
-- Whiskers <http://www.aacit.net>
-- ~~~~~~~~~~ <news:alt.autos.citroen>
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| User: "DOG" |
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| Title: Re: findings on depression |
05 Jul 2003 05:19:11 AM |
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Whiskers <catwheezel@operamail.com> wrote in message news:<17iht-08s.ln1@ID-107770.user.dfncis.de>...
In alt.support.depression on Friday 04 Jul 2003 3:06 pm, Howian
<howian@aol.com> wrote:
Want to send this story to another AOL member? Click on the heart at the
top of this window.
No hearts on my window :((
Genome survey finds depression genes
WASHINGTON, July 2 (Reuters) - U.S. researchers using the newly published
human gene map said on Wednesday they had identified 19 different genetic
regions linked with depression.
snip
Zubenko's team found some mutations seem to be sex-specific -- some for
women and at least one for men.
"Women are twice as likely as men to develop depression, and genetic
differences appear to account for some of that disparity," Zubenko said.
These could help explain why women seem more vulnerable to depression
during puberty, pregnancy and childbirth and menopause, Zubenko said.
Men seldom have Depression during pregnancy and childbirth, and I'm certain
genetics have something to do with that!
They also noticed that people in families with these genetic changes tend
to live shorter lives.
People who had died in the 81 families were eight years younger when they
died than the average for the general population, the researchers found.
Hmm ... Depression seems to run in my family, but we're a long-lived lot.
snip
Interesting. Thanks for posting it :))
'Men seldom have Depression during pregnancy and childbirth'
Male depression in these circumstances is relative to the likely
coming effect on their wallet.
xs
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| User: "Whiskers" |
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| Title: Re: findings on depression |
05 Jul 2003 09:55:48 AM |
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In alt.support.depression on Saturday 05 Jul 2003 11:19 am, DOG
<xsxsxs@freeuk.com> wrote:
snip
'Men seldom have Depression during pregnancy and childbirth'
Male depression in these circumstances is relative to the likely
coming effect on their wallet.
Indeed.
--
-- ^^^^^^^^^^ Interested in Citroens?
-- Whiskers <http://www.aacit.net>
-- ~~~~~~~~~~ <news:alt.autos.citroen>
.
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