Sociology > Education > X-"inbred" females: some real-world in put for rAD's armchair science
| Topic: |
Sociology > Education |
| User: |
"Cary Kittrell" |
| Date: |
23 Nov 2003 03:31:00 PM |
| Object: |
X-"inbred" females: some real-world in put for rAD's armchair science |
You may recall that in a previous thread "Why most geniuses are male",
our very own "rAD" proposed -- or perhaps not so much proposed as revealed,
as in "revelation" -- a rather novel thesis:
Another reason nearly all geniuses and highly inventive
people are men is that they are, in effect, inbred on the X
chromosome, having only one copy. Thus, all recessive traits
on that chromosome, both good and bad, are expressed. This
creates a greater variety of traits among males than females.
Women are, on average, more average.
In case that made everything spin and go fuzzy for you, let's try
it again:
That's why males express recessive traits on the X at a rate
that is raised to the power of 2 compared to females. In fact
all recessive traits will be expressed. This partly explains
the greater variety of traits, talents and defects among
males .
rAD accepted praise (entirely self-administered) with grace
I think my theory about males being "inbred" on the X is quite
brilliant. As far as I know, no one else has ever thought of it (or
cares about it).
but could be a bit prickly as regards criticism
Look moron, males have ONLY ONE X CHROMOSOME. THIS MAKES THEM
EFFECTIVELY 100% INBRED ON THE X, JUST LIKE A FEMALE WITH
DUPLICATE Xs, ALL RECESSIVE TRAITS WILL BE EXPRESSED.
again
LOL, this idiot obviously doesn't know the first thing about
genetics but that doesn't stop him from commented on it.
Probably a mulatto.
Apropos of all this, here's a paragraph from the current Scientific
American, from an article on epigenetic modulation of the genome:
Females...start out life with two active X chromosomes; males
inherit just one. A female embyro must muzzle the extra X to
prevent its cells from getting a double dose of X-borne genes. To
do this, two parts of the genomic machine conspire to shut down
the third. A noncoding gene named _Xist_ produces an active RNA
that coats the unneeded X chromosome, The needed X meanwhile
produces "antisense" RNA, which acts like an antidote to protect
it from _Xist_. A chain reaction spreads down the DNA, histones
shed the chemical acetyl from their tails, and the chromatin
compacts into an inaccessible, RNA-coated mass. The silent X
chromosome is then passed down, inactive, to every genome-bearing
cell as the woman grows.
Sounds like a darkly-lit scene from "Alien".
Also sounds as if females are just as (to use rAD's bajno-centric
terminology) "inbred on the X" as males are.
-- cary
[ followups set to `alt.education']
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| User: "rAD" |
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| Title: Re: X-"inbred" females: some real-world in put for rAD's armchair science |
23 Nov 2003 07:40:38 PM |
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"Cary Kittrell" <cary@afone.as.arizona.edu> wrote in message
news:bpr8uk$mn0$1@oasis.ccit.arizona.edu...
You may recall that in a previous thread "Why most geniuses are male",
our very own "rAD" proposed -- or perhaps not so much proposed as
revealed,
as in "revelation" -- a rather novel thesis:
Another reason nearly all geniuses and highly inventive
people are men is that they are, in effect, inbred on the X
chromosome, having only one copy. Thus, all recessive traits
on that chromosome, both good and bad, are expressed. This
creates a greater variety of traits among males than females.
Women are, on average, more average.
In case that made everything spin and go fuzzy for you, let's try
it again:
That's why males express recessive traits on the X at a rate
that is raised to the power of 2 compared to females. In fact
all recessive traits will be expressed. This partly explains
the greater variety of traits, talents and defects among
males .
rAD accepted praise (entirely self-administered) with grace
I think my theory about males being "inbred" on the X is quite
brilliant. As far as I know, no one else has ever thought of it (or
cares about it).
but could be a bit prickly as regards criticism
Look moron, males have ONLY ONE X CHROMOSOME. THIS MAKES THEM
EFFECTIVELY 100% INBRED ON THE X, JUST LIKE A FEMALE WITH
DUPLICATE Xs, ALL RECESSIVE TRAITS WILL BE EXPRESSED.
again
LOL, this idiot obviously doesn't know the first thing about
genetics but that doesn't stop him from commented on it.
Probably a mulatto.
Apropos of all this, here's a paragraph from the current Scientific
American, from an article on epigenetic modulation of the genome:
Females...start out life with two active X chromosomes; males
inherit just one. A female embyro must muzzle the extra X to
prevent its cells from getting a double dose of X-borne genes. To
do this, two parts of the genomic machine conspire to shut down
the third. A noncoding gene named _Xist_ produces an active RNA
that coats the unneeded X chromosome, The needed X meanwhile
produces "antisense" RNA, which acts like an antidote to protect
it from _Xist_. A chain reaction spreads down the DNA, histones
shed the chemical acetyl from their tails, and the chromatin
compacts into an inaccessible, RNA-coated mass. The silent X
chromosome is then passed down, inactive, to every genome-bearing
cell as the woman grows.
Sounds like a darkly-lit scene from "Alien".
Also sounds as if females are just as (to use rAD's bajno-centric
terminology) "inbred on the X" as males are.
LOL, tell that to all the guys with hemophilia or color blindness (or any of
the other 500 X-linked diseases). Obviously, an entire X in females is not
masked or females would have the same rate of those diseases as males do.
Please get a book on basic genetics from the library before you post again.
Don't skip the part about recessive genes.
rAD
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| User: "OhSojourner" |
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| Title: Re: X-"inbred" females: some real-world in put for rAD's armchair science |
23 Nov 2003 11:32:17 PM |
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(Cary Kittrell) wrote in message news:<bpr8uk$mn0$1@oasis.ccit.arizona.edu>...
You may recall that in a previous thread "Why most geniuses are male",
our very own "rAD" proposed -- or perhaps not so much proposed as revealed,
as in "revelation" -- a rather novel thesis:
Another reason nearly all geniuses and highly inventive
people are men is that they are, in effect, inbred on the X
chromosome, having only one copy. Thus, all recessive traits
on that chromosome, both good and bad, are expressed. This
creates a greater variety of traits among males than females.
Women are, on average, more average.
In case that made everything spin and go fuzzy for you, let's try
it again:
That's why males express recessive traits on the X at a rate
that is raised to the power of 2 compared to females. In fact
all recessive traits will be expressed. This partly explains
the greater variety of traits, talents and defects among
males .
rAD accepted praise (entirely self-administered) with grace
I think my theory about males being "inbred" on the X is quite
brilliant. As far as I know, no one else has ever thought of it (or
cares about it).
but could be a bit prickly as regards criticism
Look moron, males have ONLY ONE X CHROMOSOME. THIS MAKES THEM
EFFECTIVELY 100% INBRED ON THE X, JUST LIKE A FEMALE WITH
DUPLICATE Xs, ALL RECESSIVE TRAITS WILL BE EXPRESSED.
again
LOL, this idiot obviously doesn't know the first thing about
genetics but that doesn't stop him from commented on it.
Probably a mulatto.
Apropos of all this, here's a paragraph from the current Scientific
American, from an article on epigenetic modulation of the genome:
Females...start out life with two active X chromosomes; males
inherit just one. A female embyro must muzzle the extra X to
prevent its cells from getting a double dose of X-borne genes. To
do this, two parts of the genomic machine conspire to shut down
the third. A noncoding gene named _Xist_ produces an active RNA
that coats the unneeded X chromosome, The needed X meanwhile
produces "antisense" RNA, which acts like an antidote to protect
it from _Xist_. A chain reaction spreads down the DNA, histones
shed the chemical acetyl from their tails, and the chromatin
compacts into an inaccessible, RNA-coated mass. The silent X
chromosome is then passed down, inactive, to every genome-bearing
cell as the woman grows.
Sounds like a darkly-lit scene from "Alien".
Also sounds as if females are just as (to use rAD's bajno-centric
terminology) "inbred on the X" as males are.
Not quite:
http://citeseer.nj.nec.com/context/2029610/0
"To prevent females from receiving a double dosage of 22 X chromosome
genes, one X chromosome is suppressed in all female cells." True,
*one* chromosome is suppressed in all females cells, but note that it
does not say the SAME chromosome is suppressed in all the cells.
Rather, some cells in some parts of the body have one X chromosome
turned off while others have the other X chromosome turned off. This
is known as "mosaicing".
This occurs in all female mammals, and a good visual example of it can
be seen in the tortoiseshell cat. In cats, apparently color is linked
to the sex chromosomes, so the black and orange patchwork provides
sort of a visual map showing the randomness of the X inactivation.
Only females (and rare XXY males) can be tortoiseshell . This page
explains more:
http://arbl.cvmbs.colostate.edu/hbooks/genetics/medgen/chromo/mosaics.html
.
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| User: "rAD" |
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| Title: Re: X-"inbred" females: some real-world in put for rAD's armchair science |
24 Nov 2003 09:10:23 AM |
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"OhSojourner" <ohsojourner@aol.com> wrote in message
news:ce660175.0311232132.14d06aec@posting.google.com...
cary@afone.as.arizona.edu (Cary Kittrell) wrote in message
news:<bpr8uk$mn0$1@oasis.ccit.arizona.edu>...
You may recall that in a previous thread "Why most geniuses are male",
our very own "rAD" proposed -- or perhaps not so much proposed as
revealed,
as in "revelation" -- a rather novel thesis:
Another reason nearly all geniuses and highly inventive
people are men is that they are, in effect, inbred on the X
chromosome, having only one copy. Thus, all recessive traits
on that chromosome, both good and bad, are expressed. This
creates a greater variety of traits among males than females.
Women are, on average, more average.
In case that made everything spin and go fuzzy for you, let's try
it again:
That's why males express recessive traits on the X at a rate
that is raised to the power of 2 compared to females. In fact
all recessive traits will be expressed. This partly explains
the greater variety of traits, talents and defects among
males .
rAD accepted praise (entirely self-administered) with grace
I think my theory about males being "inbred" on the X is quite
brilliant. As far as I know, no one else has ever thought of it (or
cares about it).
but could be a bit prickly as regards criticism
Look moron, males have ONLY ONE X CHROMOSOME. THIS MAKES THEM
EFFECTIVELY 100% INBRED ON THE X, JUST LIKE A FEMALE WITH
DUPLICATE Xs, ALL RECESSIVE TRAITS WILL BE EXPRESSED.
again
LOL, this idiot obviously doesn't know the first thing about
genetics but that doesn't stop him from commented on it.
Probably a mulatto.
Apropos of all this, here's a paragraph from the current Scientific
American, from an article on epigenetic modulation of the genome:
Females...start out life with two active X chromosomes; males
inherit just one. A female embyro must muzzle the extra X to
prevent its cells from getting a double dose of X-borne genes. To
do this, two parts of the genomic machine conspire to shut down
the third. A noncoding gene named _Xist_ produces an active RNA
that coats the unneeded X chromosome, The needed X meanwhile
produces "antisense" RNA, which acts like an antidote to protect
it from _Xist_. A chain reaction spreads down the DNA, histones
shed the chemical acetyl from their tails, and the chromatin
compacts into an inaccessible, RNA-coated mass. The silent X
chromosome is then passed down, inactive, to every genome-bearing
cell as the woman grows.
Sounds like a darkly-lit scene from "Alien".
Also sounds as if females are just as (to use rAD's bajno-centric
terminology) "inbred on the X" as males are.
Not quite:
http://citeseer.nj.nec.com/context/2029610/0
"To prevent females from receiving a double dosage of 22 X chromosome
genes, one X chromosome is suppressed in all female cells." True,
*one* chromosome is suppressed in all females cells, but note that it
does not say the SAME chromosome is suppressed in all the cells.
Rather, some cells in some parts of the body have one X chromosome
turned off while others have the other X chromosome turned off. This
is known as "mosaicing".
This occurs in all female mammals, and a good visual example of it can
be seen in the tortoiseshell cat. In cats, apparently color is linked
to the sex chromosomes, so the black and orange patchwork provides
sort of a visual map showing the randomness of the X inactivation.
Only females (and rare XXY males) can be tortoiseshell . This page
explains more:
http://arbl.cvmbs.colostate.edu/hbooks/genetics/medgen/chromo/mosaics.html
I have another theory about the X. Since all males are, in effect, 100%
inbred on the X and all recessive traits are expressed, the X may be a
"proving ground" for genes which move on and off the X from other
chromosomes. Remember, males are highly expendable. There is never a
shortage of high quality sperm. By moving to the X, even a very rare
recessive gene increases it rate of expression to 100% in males. It no
longer has to "pair up" with another rare version of itself. The is no
dominant gene on the corresponding allele to mask it because that
corresponding allele doesn't exist in males. If that gene proves an
advantage, it can be rapidly spread via an "alpha male" to many offspring.
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