| Topic: |
Science > Physics |
| User: |
"Sam Wormley" |
| Date: |
15 Oct 2006 09:26:37 AM |
| Object: |
MathTrek: Knots in Proteins |
MathTrek: Knots in Proteins
http://www.sciencenews.org/articles/20061014/mathtrek.asp
Knotted proteins are rare but more than just random occurrences.
Ivars Peterson
It's amazing how easily a loosely coiled rope can acquire a knot. The
same sort of tangling can happen to a long hose lying in an untidy heap
in a garden shed, earphone cords connected to a music player, and a
necklace in a jewelry box.
Given that it normally takes some effort to create a knot, the
seemingly spontaneous formation of knots in ropes and strings can
appear puzzling.
See: http://www.sciencenews.org/articles/20061014/mathtrek.asp
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| User: "MathFreak NoMore" |
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| Title: Re: MathTrek: Knots in Proteins |
15 Oct 2006 02:06:11 PM |
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On Sun, 15 Oct 2006 14:26:37 GMT, Sam Wormley wrote:
MathTrek: Knots in Proteins
http://www.sciencenews.org/articles/20061014/mathtrek.asp
Knotted proteins are rare but more than just random occurrences.
Ivars Peterson
"A proteasome starts its job of degrading a protein
by unfolding it ¡X a task accomplished by threading
the protein through a narrow pore. "Such threading
unto the degradation chamber depends on how easily
a protein unfolds, with more stable proteins being
released back into solution and unstable ones being
degraded," Virnau, Mirny, and Kardar say."
If this is the mechanism then most proteins would be
knotted (the unfolded ones being destroyed after having
gone through the above pore). Then why is he branding
them "rare".
--
"agar barAye vatane azize khod aghabe chAreh
migardim nazar bAyad dar kolliyeye sho'une keshvar
va be tamAme afrAde mellat va dar har fardi be
joz'-joz'e a'mAle dowrAne omre 'u bAshad."
- Mehdi Bazargan
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